Apolipoprotein A-I

The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.

Also Known As:

Apolipoprotein A1; Apo A-I; Apolipoprotein AI; Apo A-1; ApoA-I; Apo A-I Isoproteins; Apo A1; Apo AI; ApoA-1; Apolipoprotein A-1; Apolipoprotein A-I Isoprotein-2; Apolipoprotein A-I Isoprotein-4; Apolipoprotein A-I Isoproteins; Apolipoprotein AI Propeptide; Pro-Apo A-I; Pro-Apolipoprotein A-I; Proapolipoprotein AI; Apo A I Isoproteins; Apolipoprotein A 1; Apolipoprotein A I; Apolipoprotein A I Isoprotein 2; Apolipoprotein A I Isoprotein 4; Apolipoprotein A I Isoproteins; Pro Apo A I; Pro Apolipoprotein A I

Lipids: 114793
- Lipoproteins: 18361
  - Apolipoproteins: 14925
    - Apolipoproteins A: 1020
      - Apolipoprotein A-I: 3926
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Lipoproteins: 18361
    - Apolipoproteins: 14925
      - Apolipoproteins A: 1020
        Apolipoprotein A-I: 3926
  - Apoproteins: 638
    - Apolipoproteins: 14925
      - Apolipoproteins A: 1020
        Apolipoprotein A-I: 3926

D E Johnstone Selected Research

D E Johnstone Research Topics

Disease

Drug/Important Bio-Agent (IBA)